Nuclear Magnetic Resonance (NMR) spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion. In order to achieve the desired results, a variety of NMR techniques are available. The basics of NMR are described here.
MRI (magnetic resonance imaging) has become a staple of medical diagnostics. Millions of Americans have had an MRI; it is a useful non-invasive and non-destructive diagnostic tool for imaging soft tissues such as the brain, heart and muscles, and for discovering tumors in many organs. MRI is an application of NMR (nuclear magnetic resonance), an analytical tool of chemists found in laboratories worldwide.
Together, NMR and MRI revolutionized the practice of chemistry and medicine by providing fast, non-destructive, and non-invasive means for the observation of matter from the atomic to the macroscopic scale.